Severe spinal cord injury (SCI) is a very debilitating and costly injury. This report presents information from the Australian Spinal Cord Injury Register (ASCIR) on 348 newly incident cases from trauma and disease in 2006-07. During the year, 272 new cases of SCI from traumatic causes were registered in Australia, an age-adjusted incidence rate of 14.9 cases per million population. The most common clinical outcome of SCI from traumatic causes was incomplete tetraplegia (98 cases). Transport related injuries (52%) and falls (29%) accounted for over three-quarters of the 271 cases of traumatic SCI (one case under the age of 15 years was excluded from these analyses). Cases also occurred during sport (n = 21) and working for income, including travel to and from work (n = 37). Falling was the most common type of event leading to traumatic SCI at older ages. The ASCIR is a collaborative activity of the AIHW National Injury Surveillance Unit and all of the specialist spinal units in Australia.